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Fig. 2 | Journal of Neurodevelopmental Disorders

Fig. 2

From: Acute administration of lovastatin had no pronounced effect on motor abilities, motor coordination, gait nor simple cognition in a mouse model of Angelman syndrome

Fig. 2

Lovastatin did not affect rotarod performance in Ube3a+/+ and Ube3a−/+ mice. A No significant effect of lovastatin was observed on the rotarod in Ube3a+/+ mice. B No significant effect of lovastatin was observed on the rotarod in Ube3a-/+ mice. C Vehicle treated Ube3a−/+ mice displayed significantly reduced latencies to fall when compared to Ube3a+/+ mice, at each time point, * p < 0.05, repeated-measures two-way ANOVA, followed by Holm-Sidak post-hoc analysis

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