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Table 2 VBM GLM results for the contrast controls > 47,xxx. Significant clusters with decreased GM volume in 47,XXX at a voxel threshold of p < .05 (FWE-corr.) and a cluster size threshold of k > 100. A complete list of significant clusters can be found in supplementary table S3

From: Brain structure in triple X syndrome: regional gray matter volume and cortical thickness in adult women with 47,XXX karyotype

Region1

Size

 

MNI coordinates

 

Peak voxel

 

mm3

 

x

y

Z

 

T

Z

p

Hippocampus L

3851

 

-29

-6

-20

 

11.29

7.43

0.00000007

Amygdala L

  

-26

-3

-30

 

10.72

7.23

0.00000033

Insula L

  

-41

11

-9

 

8.70

6.41

0.00005541

Cerebellum 8 R

4991

 

14

-72

-41

 

10.43

7.12

0.00000070

Cerebellum Crus2 R

  

9

-78

-35

 

9.40

6.72

0.00000917

Cerebellum Crus2 L

  

-8

-75

-33

 

9.35

6.70

0.00001023

Amygdala R

892

 

27

-6

-15

 

9.48

6.75

0.00000741

Amygdala R

  

29

-3

-24

 

8.85

6.48

0.00003713

Putamen R

1680

 

35

0

-3

 

8.73

6.43

0.00005028

Putamen R

  

24

6

-8

 

8.25

6.21

0.00017707

Insula R

  

38

17

-11

 

7.59

5.89

0.00102743

Cerebellum 4 5 L

112

 

-15

-33

-20

 

8.41

6.28

0.00011584

Cerebellum 4 5 L

  

-11

-38

-14

 

7.34

5.76

0.00200160

Cerebellum 9 L

112

 

-14

-44

-54

 

7.81

5.99

0.00057612

Cerebellum 9 L

  

-15

-50

-47

 

6.27

5.17

0.03485522

OFC ant R

109

 

30

48

-20

 

7.75

5.96

0.00067992

Cerebellum 9 R

299

 

5

-48

-65

 

7.65

5.92

0.00087472

Cerebellum 9 R

  

9

-53

-48

 

7.39

5.78

0.00174805

Cerebellum 9 R

  

3

-54

-71

 

7.09

5.62

0.00399479

OFC post L

235

 

-23

14

-23

 

7.57

5.87

0.00110046

OFC post L

  

-20

23

-20

 

7.43

5.80

0.00158340

OFC med L

  

-15

20

-27

 

7.01

5.58

0.00491704

OFC post R

192

 

26

27

-14

 

7.44

5.81

0.00154603

OFC med R

  

18

23

-20

 

7.16

5.66

0.00327685

OFC med R

  

17

23

-29

 

7.08

5.62

0.00402730

  1. Notes. 1 Peaks are given for cluster peak voxels and local maxima within the clusters