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Table 3 Aim 1: Model Estimates for Age, Diagnosis, Sex, BMI Percentile, and Medication on Autonomic Outcomes

From: Pubertal developmental, body mass index, and cardiovascular autonomic function in children and adolescents with and without autism spectrum disorder: a four-time point accelerated longitudinal study

Parameter

Estimate

rdf

95% CI

t

p-value

d

RSA

 Intercept

6.757

566

6.155, 7.358

22.069

 < 0.001

3.046

 Diagnosis: ASD

−0.057

234.344

−0.282, 0.169

−0.495

0.621

−0.068

 Sex: Female

−0.071

214.275

−0.293, 0.150

−0.635

0.526

−0.088

 Medication Use: Yes

−0.339

511.417

−0.527, −0.151

−3.541

 < 0.001

−0.489

 Age

0.007

551.288

−0.037, 0.050

0.3

0.765

0.041

 BMI Percentile

−0.005

368.836

−0.008, −0.002

−3.386

 < 0.001

−0.467

 σ2Error

0.507

     

 σ2Participant

0.350

     

PEP

 Intercept

58.499

498.302

52.352, 64.647

18.696

 < 0.001

2.580

 Diagnosis: ASD

0.55

219.240

−2.288, 3.388

0.382

0.703

0.053

 Sex: Female

0.569

195.277

−2.257, 3.394

0.397

0.692

0.055

 Medication Use: Yes

−0.158

511.897

−2.165, 1.849

−0.154

0.877

−0.021

 Age

3.091

430.411

2.662, 3.519

14.181

 < 0.001

1.957

 BMI Percentile

0.011

423.644

−0.024, 0.045

0.609

0.543

0.084

 σ2Error

38.131

     

 σ2Participant

69.705

     

CAB

 Intercept

−0.427

510

−1.340, 0.485

−0.919

0.358

−0.127

 Diagnosis: ASD

−0.039

230.820

−0.416, 0.337

−0.206

0.837

−0.028

 Sex: Female

0.039

206.248

−0.332, 0.410

0.207

0.837

0.029

 Medication Use: Yes

−0.346

510

−0.639, −0.053

−2.318

0.021

−0.320

 Age

0.066

467.840

0.001, 0.131

2.01

0.045

0.277

 BMI Percentile

−0.004

381.706

−0.009, 0.00

−1.801

0.073

−0.249

 σ2Error

0.934

     

 σ2Participant

1.080

     

CAR

 Intercept

1.093

500.742

0.266, 1.919

2.598

0.01

0.359

 Diagnosis: ASD

−0.021

216.858

−0.367, 0.326

−0.118

0.906

−0.016

 Sex: Female

−0.115

193.288

−0.457, 0.227

−0.661

0.509

−0.091

 Medication Use: Yes

−0.365

500.164

−0.631, −0.099

−2.691

0.007

−0.371

 Age

−0.042

454.839

−0.101, 0.017

−1.406

0.16

−0.194

 BMI Percentile

−0.006

371.400

−0.010, −0.002

−2.635

0.009

−0.364

 σ2Error

0.753

     

 σ2Participant

0.934

     
  1. Bold indicates significance at p < 0.05. rdf = residual degrees of freedom; CI = Confidence Interval; d = Cohen’s d; σ2Error = Error Variance; σ2Participant = Random Effects Variance
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Journal of Neurodevelopmental Disorders

ISSN: 1866-1955

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