Fig. 1

Example 3D volumetric reconstructions of extra-axial cerebrospinal fluid (CSF), cortical grey matter, white matter, deep grey matter structures, internal CSF filled spaces, the cerebellum and the brainstem derived from an automated fetal brain tissue segmentation pipeline (A). Examples of good quality 3D fetal brain SVRs in axial and coronal views for a healthy control fetus (B) and a fetus with 22qDS (C) along with corresponding regional segmentations are also shown