Fig. 4

Between-group differences in the global parameters of brain white matter network. The SMA group showed a significant decrease in Eglob (p = 0.01) but significant increases in Lp (p = 0.01), γ (p = 0.0497), and σ (p = 0.047) compared with the HC group. Eglob, global efficiency; Eloc, local efficiency; Cp, clustering coefficient; Lp, characteristic path length; σ = γ/λ, small-world characteristic; λ, normalized characteristic path length; γ, normalized clustering coefficient; SMA, spinal muscular atrophy; HC, health controls; *p < 0.05