Attenuated processing of vowels in the left temporal cortex predicts speech-in-noise perception deficit in children with autism

Table 2 Relationship between psychophysical and MEG results in children with ASD: Spearman partial correlation between WiN scores and adjusted SPN to periodic and non-periodic vowels

	Periodic vowels	Non-periodic vowels
Left hemisphere
WiNam	*SPNadj: Rpart =-0.55,* p = 0.005** Age: Rpart = 0.50, p = 0.013 IQ: Rpart = 0.19, p = 0.36	*SPNadj: Rpart* =-0.61, p = 0.001** Age: Rpart = 0.48, p = 0.02 IQ: R part = 0.13, p = 0.53
WiNst	SPNadj: Rpart =-0.26 p = 0.22 Age: Rpart = 0.46, p = 0.02 IQ: Rpart =-0.21, p = 0.32	SPNadj: Rpart =-0.19, p = 0.37 Age: Rpart = 0.45, p = 0.02 IQ: Rpart = -0.23, p = 0.27
Right hemisphere
WiNam	SPNadj: Rpart =-0.03, p = 0.88 Age: Rpart = 0.52, p = 0.01 IQ: Rpart = 0.10 p = 0.64	SPNadj: Rpart =-0.01, p = 0.96 Age: Rpart = 0.51, p = 0.01 IQ: Rpart = 0.11 p = 0.62
WiNst	SPNadj: R =-0.02, p = 0.92 Age: Rpart = 0.49, p = 0.01 IQ: Rpart =-0.23 p = 0.28	SPNadj: R =-0.02, p = 0.91 Age: Rpart = 0.49, p = 0.01 IQ: Rpart =-0.23 p = 0.28

WiN words-in-noise, SPNadj Sound Processing Negativity, adjusted for response to control stimuli and for the number of averaged epochs. The analysis was performed in 26 children with ASD in whom WiN + IQ + MEG data were available. Significant Spearman partial correlations of interest which survive Bonferroni correction for multiple comparison (uncorrected p < 0.00625) are marked in bold. P-values are two-tailed, uncorrected for multiple comparisons

ISSN: 1866-1955