Table 2 Psychiatric diagnostic rates in XXY/KS and XYY
DSM-V Diagnosis (K-SADS) | Disorder Prevalence, n (%) | Chi-square comparison | Logistic regression model (covarying for age & IQ) | |||
|---|---|---|---|---|---|---|
XXY/KS | XYY | Chi-square statistic | p-value | β for SCA group (XYY) | p-value | |
Any disorder (d/o) | 89 (87) | 56 (88) | 0.53 | 0.47 | -0.39 | 0.46 |
Any neurodevelopmental d/o | 80 (78) | 50 (78) |  < .0001 | 1 | -0.25 | 0.55 |
Autism spectrum d/o | 33 (34) | 9 (14) | 6.77 | 0.01 | -1.23 | 0.007 |
Attention-deficit hyperactivity d/o | 66 (65) | 43 (67) | 0.01 | 0.94 | -0.11 | 0.76 |
Tic d/o | 7 (7) | 10 (16) | 2.33 | 0.13 | 1.31 | 0.02 |
Intellectual Disability | 1 (1) | 6 (9) | - | - | - | - |
Obsessive–compulsive d/o | 2 (2) | 2 (3) | - | - | - | - |
Any elimination d/o | 27 (27) | 21 (32) | 0.44 | 0.51 | 0.17 | 0.66 |
Enuresis | 26 (26) | 20 (30) | 0.35 | 0.55 | 0.17 | 0.66 |
Encopresis | 1 (< 1) | 4 (< 1) | - | - | - | - |
Any mood d/o | 18 (18) | 10 (16) | 0.02 | 0.88 | 0.06 | 0.89 |
Bipolar d/o | 1 (< 1) | - | - | - | - | - |
Depressive d/o | 12 (12) | 5 (8) | 0.33 | 0.57 | 0.03 | 0.96 |
Disruptive mood dysregulation d/o | 5(5) | 6 (9) | - | - | 0.25 | 0.71 |
Any anxiety d/o | 33 (33) | 6 (9) | 10.53 | 0.001 | -1.47 | 0.003 |
Any trauma- or stress-related d/o | 7 (7) | 1 (2) | - | - | - | - |
Reactive attachment d/o | - | - | - | - | - | - |
Post-traumatic stress d/o | 7 (7) | 1 (2) | - | - | - | - |
Any disruptive/impulse-control d/o | 4 (4) | 5 (8) | - | - | 0.75 | 0.31 |
Oppositional defiant d/o | 4 (4) | 4 (6) | - | - | 0.4 | 0.61 |
Conduct d/o | - | - | - | - | - | - |
Intermittent explosive d/o | - | 1 (2) | - | - | - | - |
Substance use d/o | 1 (< 1) | - | - | - | - | - |